Domperidone where to get

If you do live in the United States, compounding pharmacies used to be an option, but the FDA got more oversight over them in , and therefore, many no longer make the drug. However, if there is a compounding pharmacy near you , you can call and ask what their policy on making domperidone is. Per Dr. Newman, who is a breastfeeding expert, the other option is ordering from an international pharmacy here are the FDA regulations for doing this.

This drug is approved by the FDA. The downside to Reglan is that depression is a side effect. Since new mothers are susceptible to post-partum depression, taking a drug with this side effect may be contraindicated, especially if you have a family or personal history of depression.

Breastfeeding supplements and herbal galactagogues, like fenugreek and blessed thistle , are other options. When you get your prescriptions, you should confirm with your doctor that you can take it without any issues, and that there are no interactions with any other medications you may be taking. You should wean off of it. A sample weaning schedule is available here. She analysed the macronutrient content with respect to protein, fat, carbohydrate and energy and macro mineral content of sodium, phosphorous and calcium of 44 women taking either 10mg three times a day of domperidone or placebo.

Domperidone increased the volume of breast milk without substantially altering the nutrient composition. In the DaSilva study 10 20 women in a double-blind, placebo-controlled protocol. Those prescribed domperidone 10mg three times a day showed a steady increase in milk production over placebo.

Mothers received counselling support and were double pumping. The increase in production achieved fell once the drug was stopped after seven days. The babies in the study were all in neonatal intensive care and the mothers were only expressing for feeds to be given via naso-gastric tube. The increase in milk volume began 48 hours after the drug was initiated and continued to the end of the trial. The study was stopped after seven days when most mothers began some level of direct breastfeeding, at which point it became impractical to measure breastmilk volume.

Only one study looked at mothers who had not delivered prematurely One month after the study began all treated women had adequate milk production, but none of those who had not been treated with domperidone had achieved an increase in milk supply above that at the beginning of the trial.

Wan et al 14 studied seven mothers who had delivered pre-term in a double-blind, randomised cross-over study. They used two dose regimes — 10mg or 20mg three times a day.

One mother taking the 20mg dose withdrew early because of severe abdominal cramps. Two others failed to respond to either dose. In four mothers, there was a significant increase in prolactin level and milk volume, with a greater response at the higher dose in three of these women.

Side effects noted included abdominal cramping, constipation, dry mouth, depressed mood and headache, which were more apparent with the higher dose.

Wan et al concluded that if there is no response at a 10mg dose, there is no point in further increasing the dose. This is at variance to the information in the consensus statement 8. Reproduced from Ingram Mothers produced more milk in the domperidone group and achieved a mean of This difference was not statistically significant.

Ten women Headache by 1 on domperidone 3 on metoclopramide, 1 on each medication reported diarrhoea, one on each mood swings, one mother on domperidone reported dizziness. Other effects reported by the metoclopramide cohort were change in appetite, dry mouth, and tingling, stinging, uncomfortable breasts. Only one woman stopped taking the trial medication metoclopramide after 5 days due to bad headaches and dry mouth; all the others tolerated any side effects as they were keen to keep their increased milk production going.

DaSilva 16 reported average milk concentrations ranged from 1. No adverse events were noted in mothers or children. Domperidone is subject to extensive first pass metabolism which accounts for the low transfer into breastmilk. The mean relative infant dose was 0.

Hale 17 quotes a relative infant dose range of 0. There are no studies that provide an evidence base on how long to continue domperidone in the case of inadequate lactation Anecdotally, some women feel that their supply cannot be maintained without the drug, while some can reduce the dose but not stop altogether.

It is possible that domperidone is acting as a placebo to boost their confidence — we do not know and should admit the limitations of the research. Updated: September The primary source for the information in this leaflet is the published articles on domperidone use in improving milk supply. For details on any other sources used to create this leaflet, please contact us via CHQMedicationSafety health. We take great care to make sure that the information in this leaflet is correct and up-to-date.

However, medicines can be used in different ways for different patients. It is important that you ask the advice of your doctor or pharmacist if you are not sure about something. This leaflet is about the use of these medicines in Australia, and may not apply to other countries.

Research and education. Back to medicines fact sheets. Domperidone for improving breast milk supply fact sheet. If you are taking any other medication, including over the counter or complementary medicines also known as traditional or alternative medicines including vitamins, minerals, herbs, aromatherapy and homeopathic products from a health food store, discuss this with your doctor prior to commencing domperidone.

General advice about medicines Try to take the medicine at about the same times each day. This will help you remember to take it every day. Taking domperidone on an empty stomach does allow it to be better absorbed, but it is not necessary to do this for it to work to increase breastmilk production. Spread the doses out throughout the day and take it when it is most convenient for you. Mothers do not have time to make sure they take the domperidone at exactly such and such time.

After starting domperidone, it often takes at least three or four days before you notice any effect. It usually takes about two weeks to get a maximum effect, but some find it takes even longer. A baby who is not getting enough from the breast, will not refuse the second breast.

As with all medications, side effects are possible. There is no such thing as a drug that has no side effects. However, in our clinical experience, side effects in the breastfeeding mother are very uncommon.

Most of those who experience side effects find they disappear after a few days to a week of starting the domperidone. The amount of domperidone that gets into the breastmilk is very small and side effects in the baby should not be expected. Domperidone is sometimes given to babies with reflux and the amount they get through the milk is a very small percentage of what they would get if they were treated with domperidone directly.

As a general recommendation, continue taking domperidone until your baby is well established on solid foods. Some people continue domperidone for many months and some beyond a year.

Worldwide experience with domperidone over at least 40 years suggests that long-term side effects are uncommon. The one therapeutic exception to taking the domperidone until the baby is well established on solids is when we use it for the baby who not latching on and the mother already has a very good milk supply.